CHO LAB PUBLICATIONS

  • Selected Publications
  • Publication List

Selected Publications

  • Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser, Exp Mol Med

    Hoyoung Kim, Taehyun Lim, Go Run Ha, Jee-Young Lee, Jun-Woo Kim, Nienping Chang, Si Hyun Kim, Ki Hun Kim, 

    Jaeick Lee, Yongju Cho, Byeong Wook Kim, Alva Abrahamsson, Sung Hwan Kim, Hyo-Ji Kim, Shan Park, Sang Jae Lee, 

    Jaehyun Park, Eunhi Cheong, B. Moon Kim, Hyun-Soo Cho*

    Article
  • A novel therapeutic anti-ErbB3, ISU104 exhibits potent anti-tumorigenic activity by inhibiting
    ligand binding and ErbB3 heterodimerizatio, Molecular Cancer Therapeutics

    Mirim Hong, Youngki Yoo, Miyoung Kim, Ju Yeon Kim, Jeong Seok Cha, Myung Kyung Choi, Uijin Kim, Kyungyong Kim,

    Youngsoo Sohn, Donggoo Bae, Hyun-Soo Cho*, Seoung-Beom Hong* (*co-correspondence)

    Article
  • Computationally-guided design and affinity improvement of a protein binder targeting a
    specific site on HER2, Computational and structural biotechnology journal

    Tae Yoon Kim, Jeong Seok Cha, Hoyoung Kim, Yoonjoo Choi, Hyun-Soo Cho*, Hak-Sung Kim(*co_correspondence)

    Article
  • Direct binding of TFEα opens DNA binding cleft of RNA polymerase Nature Communications

    Sung-Hoon Jun, Jaekyung Hyun, Jeong Seok Cha, Hoyoung Kim, Michael S Bartlett, Hyun-Soo Cho*,

    Katsuhiko S Murakami* (*co_correspondence)

    Article
  • Enzymatic Prenylation and Oxime Ligation for the Synthesis of Stable and Homogeneous
    Protein–Drug Conjugates for Targeted Therapy Angewandte Chemie

    Joong-jae Lee, Hyo-Jung Choi, Misun Yun, YingJin Kang, Ji-Eun Jung, Yiseul Ryu, Tae Yoon Kim, Young-je Cha, Hyun-Soo
    Cho*, Jung-Joon Min*, Chul-Woong Chung* and Hak-Sung Kim*,

    Article
  • GC1118, an anti-EGFR antibody with a distinct binding epitope and superior inhibitory activity
    against high-affinity EGFR ligands Molecular Cancer Therapeutics

    Yangmi Lim, Jiho Yoo, Min-Soo Kim, Minkyu Hur, Eun Hee Lee, Hyung-Suk Hur, Jae-Chul Lee, Shi-Nai Lee, Tae Wook Park, Kyuhyun
    Lee, Ki Hwan Chang, Kuglae Kim, YingJin Kang, Kwang-Won Hong, Se-Ho Kim, Yeon-Gil Kim, Yeup Yoon, Do-Hyun Nam, Heekyoung
    Yang, Dong Geon Kim, Hyun-Soo Cho*, and Jonghwa Won*

    Article
  • Crystal structure and functional characterization of a light-driven chloride
    pump having an NTQ motif

    Kuglae Kim, Soon-Kyeong Kwon, Sung-Hoon Jun, Jeong Seok Cha, Hoyoung Kim, Weontae Lee, Jihyun F. Kim* and Hyun-Soo Cho*

    Article
  • Structural basis for arginine glycosylation of host substrates by bacterial effector proteins

    Jun Bae Park, Young Hun Kim, Youngki Yoo, Juyeon Kim, Sung-Hoon Jun, Jin Won Cho, Samir El Qaidi, Samuel Walpole,
    Serena Monaco, Ana A. García-García, Miaomiao Wu, Michael P. Hays, Ramon Hurtado-Guerrero*,
    Jesus Angulo*, Philip R. Hardwidge, Jeon-Soo Shin* and Hyun-Soo Cho*

    Article

Publication List

  • 103. Tae-Geun Yu, Jeong Seok Cha, Hijeong Kim, You-Kyoung Sohn, Youngki Yoo, Uijin Kim, Ji-Joon Song, Hyun-Soo Cho, Had-Sung Kim. Oligomeric states of ASC specks regulate inflammatory responses by inflammasome in the extracellular space. Cell Death Discov. 9, 142 (2023). 
  • 102. Ji Woong Kim, Hyun Hen, Hyun Jung Kim, Youngki You, Hyun-Soo Cho, Hui Gong Jang, Ho-Young Lee, In Young Ko, Ju Rand Woo, Yea Bin Cho, Ji Hyun Lee, Ha Rim Yang, Ha Gyeong Shin, Hey Lim Choi, Kyusang Twang, Sakho Kim, Hanseong Kim, Kwangrok Chun, Sukmook Lee. "Novel bispecific human antibody platform specifically targeting a fully open spike conformation potently neutralizes multiple SARS-CoV-2 variants." Antiviral Research212 (2023): 105576
  • 101.Bo-Seong JeongJeong Seok ChaInsu HwangUijin KimJared Adolf-BryfogleBrian CoventryHyun-Soo ChoKyun-Do Kim & Byung-Ha Oh (2022) Computational design of a neutralizing antibody with picomolar binding affinity for all concerning SARS-CoV-2 variants, mAbs, 14:1,
  • 100. Yeseul Choi, Eunji Jeong, Dong-Gi Lee, Jae-Hyung Jin, Yee-Seul So, Seong-Ryoung Yu, Kyung-Jo Lee, Yoonjie Ha, Chi-Han Lin, Ying-Lien Chen, Jun Bae Park, Hyun-Soo Cho, Anna F. Averette, Joseph Heltman, Jyu-Ho Lee, Kangseok Lee, Yong-Sun Bahn. "Unraveling the Pathobiological Role of the Fungal KEOPS Complex in Cryptococcus neoformans" mBio volume 13, Issue6, e02944-22
  • 99. Eunhee Koh, Uijin Kim, and Hyun-Soo Cho, " Catalytic DxD motif caged in Asx-turn and Met–aromatic interaction attenuates the pathogenic glycosylation of SseK2/NleB2 effectors" Scientific Reports volume 12, Article number: 19288 (2022.11) 
  • 98. Soyeon Jeong, Jinsook Ahn, Inseong Jo, So-Mi Kang, Bum-Joon Park, Hyun-Soo Cho, Yong-Hak Kim, Nam-Chul Ha, “Cyclin-Dependent Kinase 1 depolymerizes nuclear lamin filaments by disrupting the head-to-tail interaction of the lamin central rod domain” JBC, 298(9) (2022.09)
  • 97. Bo-Seong Jeong , Jeong Seok Cha, Insu Hwang, Uijin Kim , Jared Adolf-Bryfogle, Brian Coventry , Hyun-Soo Cho , Kyun-Do Kim and Byung-Ha Oh, “Computational design of a neutralizing antibody with picomolar binding affinity for all concerning SARS-CoV-2 variants” Mab, 14(1) (2022.01)
  • 96. Yunseok Heo, Hyeongseop Jeong, Youngki Yoo, Ji-Hye Yun, Bumhan Ryu, Young-je Cha, Bo-Ram Lee, Ye-Eun Jeon, Jongmin Kim, Sojin Jeong, Eunji Jo, Jae-Sung Woo, Jeewon Lee*, Hyun-Soo Cho* and Weontae Lee*, “Structural and Functional Characterizations of Cancer Targeting Nanoparticles Based on Hepatitis B Virus Capsid” International Journal of Molecular Sciences, 22, 9140 (2021.10)
  • 95. Seok-Jun Kim, Hyeok-Gu Kang, Kyungeun Kim, Hoyoung Kim, Fredrik Zetterberg, Young Soo Park, Hyun-Soo Cho, Stephen M Hewitt, Joon-Yong Chung, Ulf J Nilsson, Hakon Leffler, Kyung-Hee Chun, “Crosstalk between WNT and STAT3 is mediated by galectin-3 in tumor progression” Gastric Cancer, 24(5), 1050-1062 (2021.09)
  • 94. Roshan D’Souza, Le Phuong Nguyen, Naina A. Pinto, Hyunsook Lee, Thao Nguyen Vu, Hoyoung Kim, Hyun Soo Cho & Dongeun Yong, “Role of AmpG in the resistance to β-lactam agents, including cephalosporins and carbapenems: candidate for a novel antimicrobial target” Annals of Clinical Microbiology and Antimicrobials, 20, 45 (2021.06)
  • 93. Ji Hyeon Kim, Jeeyoung Lee, Won Hoon Choi, Seoyoung Park, Seo Hyeong Park, Jung Hoon Lee, Sang Min Lim, Ji Young Mun, Hyun-Soo Cho, Dohyun Han, Young Ho Suh and Min Jae Lee, “CHIP-Mediated Hyperubiquitylation of Tau Promotes Its Self-Assembly into the Insoluble Tau Filaments” Chemical Science, 12 (2021.04) (IF 9.4)
  • 92. Mirim Hong, Youngki Yoo, Miyoung Kim, Ju Yeon Kim, Jeong Seok Cha, Myung Kyung Choi, Uijin Kim, Kyungyong Kim, Youngsoo Sohn, Donggoo Bae, Hyun-Soo Cho* Seung-Beom Hong*"A novel therapeutic anti-ErbB3, ISU104 exhibits potent anti-tumorigenic activity by inhibiting ligand binding and ErbB3 heterodimerization” Molecular Cancer Therapeutics, ###,### (2021.04)  (*co_correspondence)
  • 91. Tae Yoon Kim, Jeong Seok Cha, Hoyoung Kim, Yoonjoo Choi, Hyun-Soo Cho*, Hak-Sung Kim*, “Computationally-guided design and affinity improvement of a protein binder targeting a specific site on HER2” Computational and structural biotechnology journal, 19, 1325-1334 (2021.03) (*co_correspondence)

  • 90. Eunhee Koh, Hyun-Soo Cho* “NleB/SseKs ortholog effectors as a general bacterial monoglycosyltransferase for eukaryotic proteins” Current Opinion in Structural Biology, 68, 215-223 (2021.03)
  • 89. Sung-Hoon Jun, Jaekyung Hyun, Jeong Seok Cha, Hoyoung Kim, Michael S Bartlett, Hyun-Soo Cho*, Katsuhiko S Murakami* “Direct binding of TFEα opens DNA binding cleft of RNA polymerase’ Nature Communications, 11(1), 1-12 (2020.11) (*co_correspondence)
  • 88. Keondo Lee, Donghyeon Lee, Sangwon Baek, Jaehyun Park, Sang Jae Lee, Sehan Park, Wan Kyun Chung, Jong-Lam Lee, Hyun-Soo Cho, Yunje Cho, Ki Hyun Nam “Viscous‐medium‐based crystal support in a sample holder for fixed‐target serial femtosecond crystallography” Journal of Applied Crystallography, 53, 1051-1059 (2020.06)
  • 87. Ilyeong Choi, Young Jeon, Youngki Yoo, Hyun-Soo Cho and Hyun-Sook Pai “The in vivo functions of ARPF2 and ARRS1 in ribosomal RNA processing and ribosome biogenesis in Arabidopsis” Journal of Experimental Botany, 71(9), 2596–2611 (2020.04)

  • 86. Nayoung Kim, Daseul Cho, Hyunjin Kim, Sujin Kim, Young-je Cha, Heidi Greulich, Adam Bass, Hyun-Soo Cho and Jeonghee Cho “Colorectal adenocarcinoma-derived EGFR mutants are oncogenic and sensitive to EGFR-targeted monoclonal antibodies, cetuximab and panitumumab” International Journal of Cancer, 146(8), 2194-2200 (2020.04)
  • 85. Belinda X. Ong, Youngki Yoo, MyeongGil Han, Jun Bae Park, Myung Kyung Choi, Yeseul Choi, Jeon-Soo Shin, Yong-Sun Bahn and Hyun-Soo Cho “Structural analysis of fungal pathogenicity-related casein kinase α subunit, Cka1, in the human fungal pathogen Cryptococcus neoformans” Scientific Reports, 9(1), 1-13 (2019.10)
  • 84. Yeon Uk Ko, Su-Jeong Kim, Juhyung Lee, Min-Young Song, Kang-Sik Park, Jun Bae Park, Hyun-Soo Cho and Young J. Oh “Protein kinase A-induced phosphorylation at the Thr154 affects stability of DJ-1” Parkinsonism & Related Disorders, 66, 143-150 (2019.09)
  • 83. Jun Bae Park, Hayeong Park, Jimin Son, Sang-Jun Ha and Hyun-Soo Cho “Structural Study of Monomethyl Fumarate-Bound Human GAPDH” Molecules and Cells, 42(8), 597-603 (2019.08)
  • 82. Sunok Moon, Lae-Hyeon Cho, Yu-Jin Kim, Yun-Shil Gho, Ho Young Jeong, Woo-Jong Hong, Chanhui Lee, Hyon Park, Nam‐Soo Jwa, Sarmina Dangol, Yafei Chen, Hayeong Park, Hyun-Soo Cho, Gynheung An and Ki-Hong Jung “RSL Class Ⅱ Transcription Factors Guide the Nuclear Localization of RHL1 to Regulate Root Hair Development” Plant Physiology, 179(2), 558-568 (2019.02)
  • 81. Ji-Hye Yun*, Xuanxuan Li*, Jae-Hyun Park, Yang Wang, Mio Ohki, Zeyu Jin, Wonbin Lee, Sam-Yong Park, Hao Hu, Chufeng Li, Nadia Zatsepin, Mark S. Hunter, Raymond G. Sierra, Jake Koralek, Chun Hong Yoon, Hyun-Soo Cho, Uwe Weierstall, Leihan Tang, Haiguang Liu* and Weontae Lee* “Non-cryogenic structure of a chloride pump provides crucial clues to temperature-dependent channel transport efficiency” Journal of Biological Chemistry, 294(3), 794-804 (2019.01)
  • 80. Jun Bae Park, Youngki Yoo and Hyun-Soo Cho “Structural insights showing how arginine is able to be glycosylated by pathogenic effector proteins” BMB Reports, 51(12), 609-610 (2018.12)
  • 79. Jun Bae Park, Young Hun Kim, Youngki Yoo, Juyeon Kim, Sung-Hoon Jun, Jin Won Cho, Samir El Qaidi, Samuel Walpole, Serena Monaco, Ana A. García-García, Miaomiao Wu, Michael P. Hays, Ramon Hurtado-Guerrero*, Jesus Angulo*, Philip R. Hardwidge, Jeon-Soo Shin* and Hyun-Soo Cho* “Structural basis for arginine glycosylation of host substrates by bacterial effector proteins” Nature Communications, 9(4283) (2018.10) (*co_correspondence)
  • 78. Kuglae Kim, Jeong Seok Cha, Jin-Sik Kim, Jinsook Ahn, Nam-Chul Ha*and Hyun-Soo Cho * “Crystal structure of GSK3b in complex with the flavonoid, morin” Biochemical and Biophysical Research Communications, 504, 519-524 (2018.10) (*co_correspondence)
  • 77. Inhye Lee, Kuglae Kim, Sumin Lee, Seungjun Lee, Eunjin Hwang, Kihye Shin, Dayoung Kim, Jungki Choi, Hyunmo Choi, Jeong Seok Cha, Hoyoung Kim, Rin-A Lee, Suyeong Jeong, Jeongsik Kim, Yumi Kim, Hong Gil Nam, Soon-Ki Park, Hyun-Soo Cho and Moon-Soo Soh “Functional analysis of a missense allele of KARRIKIN-INSENSITIVE2 that impairs ligand-binding and downstream signaling in Arabidopsis thaliana” Journal of Experimental Botany, 69, 15, 3609-3623 (2018.06)
  • 76. Kuglae Kim, Jeong Seok Cha, Yong-Soon Cho, Hoyoung Kim, Nienping Chang, Hye-Jung Kim and Hyun-Soo Cho “Crystal structure of human dual-specificity tyrosine-regulated kinase 3 reveals new structural features and insights into its auto-phosphorylation” Journal of Molecular Biology 430, 10, 1521-1530 (2018.05)
  • 75. Jun Bae Park, Youngki Yoo, Belinda Xiang Yu Ong, Juyeon Kim and Hyun-Soo Cho “Purification, crystallization and X-ray diffraction of heparin sulfate bounded human RAGE” Biodesign, 5(3), 122-125 (2017.09)
  • 74. Sung Yong Ahn, Nam Hee Kim, Kyungro Lee, Yong Hoon Cha, Ji Hye Yang, So Young Cha, Eunae Sandra Cho, Yoonmi Lee, Jeong Seok Cha, Hyun Soo Cho, Yoon Jeon, Young-Su Yuk, Suebean Cho, Kyoung Tai No, Hyun Sil Kim, Ho Lee, Jiwon Choi and Jong In Yook “Niclosamide is a potential therapeutics for familial adenomatosis polyposis by disrupting Axin-GSK3 interaction.” Oncotarget 2017, 8, 31842-31855 (2017.05)
  • 73. Sang-Woo Han, Juyeon Kim, Hyun-Soo Cho and Jong-Shik Shin “Active Site Engineering of ω-Transminase Guided by Docking Orientation Analysis and Virtual Activity Screening” ACS Catalysis 2017, 7, 3752-3762 (2017.04)
  • 72. Eun-Kyung Kwon, Chan-Ki Min, Yuri Kim, Jae-Won Lee, Abdimadiyeva Aigerim, Sebastian Schmidt, Hyun-Jun Nam, Seong Kyu Han, Kuglae Kim, Jeong Seok Cha, Hoyoung Kim, Sanguk Kim, Hyun-Soo Cho, Myung-Sik Choi and Nam-Hyuk Cho “Constitutive activation of T cells by γ2-herpesviral GPCR through the interaction with cellular CXCR4.” BBA - Molecular Cell Research 1864(1), 1-11 (2017.01)
  • 71. Youngsil Choi, Ji-Hye Yun, Jiho Yoo, Inhwan Lee, Heeyoun Kim, Hye-Nam Son, In-San Kim, Ho Sup Yoon, Pascale Zimmermann, John R. Couchman, Hyun-Soo Cho, Eok-Soo Oh & Weontae Lee “New structural insight of C-terminal region of Syntenin-1, enhancing the molecular dimerization and inhibitory function related on Syndecan-4 signaling” Scientific reports 6, 36818 (2016.11)
  • 70. Kuglae Kim, Soon-Kyeong Kwon, Sung-Hoon Jun, Jeong Seok Cha, Hoyoung Kim, Weontae Lee, Jihyun F. Kim* and Hyun-Soo Cho* “Crystal structure and functional characterization of a light-driven chloride pump having an NTQ motif” Nature Communications, 7(12677) (2016.08) (*co_correspondence)
  • 69. Ji-Sun Kim, Dong-Ki Choi, Ju-Yeon Shin, Seung-Min Shin, Seong-Wook Park, Hyun-Soo Cho, Yong-Sung Kim “Endosomal acidic pH-induced conformational changes of a cytosol-penetrating antibody mediate endosomal escape.” Journal of Controlled Release, 235, 165-175 (2016.08)
  • 68. Jiyoon Kim, Shin Hye Noh, He Piao, Dong Hee Kim, Kuglae Kim, Jeong Seok Cha, Woo Young Chung, Hyun-Soo Cho, Joo Young Kim and Min Goo Lee “Monomerization and ER Relocalization of GRASP Is a Requisite for Unconventional Secretion of CFTR” Traffic, 17(7), 733-753 (2016.07)
  • 67. Yuri Kim, Shinhye Cheon,Chan-Ki Min, Kyung Mok Sohn, YingJin Kang, Young-Je Cha, Ju-Il Kang, Seong Kyu Han, Na-Young Ha,Gwanghun Kim, Abdimadiyeva Aigerim, Hyun Mu Shin, Myung-Sik Choi, Sanguk Kim, Hyun-Soo Cho, Yeon-Sook Kim, and Nam-Hyuk Cho “Spread of Mutant Middle East Respiratory Syndrome Coronavirus with Reduced Affinity to Human CD26 during the South Korean Outbreak.”, mBIO, 7(2), 1-8 (2016.03)
  • 66. Yangmi Lim, Jiho Yoo, Min-Soo Kim, Minkyu Hur, Eun Hee Lee, Hyung-Suk Hur, Jae-Chul Lee, Shi-Nai Lee, Tae Wook Park, Kyuhyun Lee, Ki Hwan Chang, Kuglae Kim, YingJin Kang, Kwang-Won Hong, Se-Ho Kim, Yeon-Gil Kim, Yeup Yoon, Do-Hyun Nam, Heekyoung Yang, Dong Geon Kim, Hyun-Soo Cho*, and Jonghwa Won*, “GC1118, an anti-EGFR antibody with a distinct binding epitope and superior inhibitory activity against high-affinity EGFR ligands” , Molecular Cancer Therapeutics, 15(2), 251-263 (2016.02) (*co_correspondence)
  • 65. Young Hun Kim, Man Sup Kwak, Jun Bae Park, Shin-Ae Lee, Ji Eun Choi, Hyun-Soo Cho*, and Jeon-Soo Shin* “N-linked glycosylation plays a critical role for the secretion of HMGB1”, Journal of Cell Science, 129(1), 29-38 (2016.01) (*co_correspondence)
  • 64. Gyongseon Yang, Wei Zhu, Kuglae Kim, Soo Young Byun, Gahee Choi, Ke Wang, Jeong Seok Cha, Hyun-Soo Cho, Eric Oldfield and Joo Hwan No “In Vitro and In Vivo Investigation of the Inhibition of Trypanosoma brucei Cell Growth by Lipophilic Bisphosphonates”, Antimicrobial agents and chemotherapy, 59(12), 7530-7539 (2015.12)
  • 63. Joong-jae Lee, Hyo-Jung Choi, Misun Yun, YingJin Kang, Ji-Eun Jung, Yiseul Ryu, Tae Yoon Kim, Young-je Cha, Hyun-Soo Cho*, Jung-Joon Min*, Chul-Woong Chung* and Hak-Sung Kim*, “Enzymatic Prenylation and Oxime Ligation for the Synthesis of Stable and Homogeneous Protein–Drug Conjugates for Targeted Therapy” Angewandte Chemie, 54(41), 12020-12024 (2015.10) (* co_correspondence)
  • 62. Heeyoun Kim, Jiho Yoo, Inhwan Lee, Ying Jin Kang, Hyun-Soo Cho* and Weontae Lee* , “Crystal structure of syndesmos and its interaction with Syndecan-4 proteoglycan” Biochemical and Biophysical Research Communications, 463, 762-767 (2015.07) (* co_correspondence)
  • 61. Sun Ah Jeong, Kuglae Kim, Ji Hoon Lee, Jeong Seok Cha, Prabhat Khadka, Hyun-Soo Cho* and In Kwon Chung* “Akt-mediated phosphorylation increases the binding affinity of hTERT for importin α to promote nuclear translocation” Journal of Cell Science, 128(12), 2287-301 (2015.06) (* co_correspondence)
  • 60. Ji-Hye Yun, Minsup Kim, Kuglae Kim, Dongju Lee, Youngjin Jung, Daeseok Oh, Yoon-Joo Ko, Art E. Cho, Hyun-Soo Cho and Weontae Lee “Solution structure of the transmembrane 2 domain of the human melanocortin-4 receptor in sodium dodecyl sulfate (SDS) micelles and the functional implication of the D90N mutant” Biochimica et Biophysica Acta, 1848, 1294-1302 (2015.03)
  • 59. Kuglae Kim, Jin-Sik Kim, Jeong Seok Cha, Hyun-Soo Cho* and Nam-Chul Ha*“Structural analysis of mouse GSK3β fused with the LRP6 peptide” Bio Design, 3(1), 55-60 (2015.03) (* co_correspondence)
  • 58. Ji-Hye Yun, Kuglae Kim, Youngjin Jung, Jae-Hyun Park, Hyun-Soo Cho* and Weontae Lee “Co-expression of human agouti-related protein enhances expression and stability of human melanocortin-4 receptor” Biochemical and Biophysical Research Communications, 456, 116-121 (2015.01) (* co_correspondence)
  • 57. Ji Won Jung, Sang ah Kim, Eun Min Kang, Tae-im Kim, Hyun-Soo Cho, and Eung Kweon Kim “Lattice Corneal Dystrophy Type IIIA with Hyaline Component from a Novel A620P Mutation and Distinct Surgical Treatments” Cornea, 33(12), 1324-1331 (2014.12)
  • 56. Yoon Sup Choi, Soomin Yoon, Kyung-Lock Kim, Jiho Yoo, Parkyong Song, Minsoo Kim, Young-Eun Shin, Won Jun Yang, Jung-eun Noh, Hyun-Soo Cho, Sanguk Kim, Jungho Chung, Sung Ho Ryu “Computational Design of Bingding Proteins to EGFR Domain II” Plos one. 9(4) e92513 (2014.04)
  • 55. Yong-Soon Cho, YingJin Kang, Kuglae Kim, Young-je Cha and Hyun-Soo Cho “The crystal structure of MPK38 in complex with OTSSP167, an orally administrative MELK selective inhibitor” Biochemical and Biophysical Research Communications, 447, 7-11 (2014, 04)
  • 54. Kuglae Kim, Yingjin Kang and Hyun-Soo Cho “Current advances in the development of G-Protein-coulped receptor structure and their future application in drug design” Bio Design. 2(1) 21-25 (2014.03)
  • 53. Yong-Soon Cho, Jiho Yoo, Soomin Park and Hyun-Soo Cho “The structures of the kinase domain and UBA domain of MPK38 suggest the activation mechanism for kinase activity” Acta Cryst. D70, 514-521 (2014.02)
  • 52. Si-Hyeon Um, Jin-Sik Kim, Kuglae Kim, Nahee Kim, Hyun-Soo Cho and Nam-Chul Ha “Structural Basis for the Inhibition of Human Lysozyme by PliC from Brucella abortus” Biochemistry. 23;52(51), 9385-93 (2013.12)
  • 51. Bo-Young Yoon, Yong-Hak Kim, Nahee Kim, Bo-Young Yun, Jin-Sik Kim, Joon-Hee Lee, Hyun-Soo Cho, Kangseok Lee and Nam-Chul Ha “Structure of the periplasmic copper-binding protein CueP from Salmonella enterica serovar Typhimurium” Acta Cryst. D69 (2013), 1867–1875 (2013.10)
  • 50. Hyun-Soo Kim, Se-Hyuk Kim, Hye-Young Park, Janet Lee, Jong Hyuk Yoon, Sunkyu Choi, Sung Ho Ryu, Ho Lee, Hyun Soo Cho and Chang-Woo Lee “Functional interplay between Aurora B kinase and Ssu72 phosphatase regulates sister chromatid cohesion” Nature communications (2013) 4:2631 (2013.10)
  • 49. Ki-Woong Jeong, Hyunsook Ko, Sung-Ah Lee, Eunmi Hon1, Sunggeon Ko, Hyun-Soo Cho, Weontae Lee, and Yangmee Kim* “Backbone Dynamics of an Atypical Orphan Response Regulator Protein, Helicobacter pylori 1043” Molecules and Cells. 35(2), 158-165 (2013.02)
  • 48. Shin-Ae Kang, Hyun-Soo Cho, Jong Bok Yoon, In Kwon Chung, and Seung-Taek Lee* “Hsp90 rescues PTK6 from proteasomal degradation in breast cancer cells” Biochem J. 447(2), 313-20 (2012.10)
  • 47. Ji-ho Yoo, Sunggeon Ko, Dong Uk Kim, Jin-Won Jung, Bon-kyung Koo, Cheryl H Arrowsmith, Henry M Krause, Hyun-Soo Cho* and Weontae Lee* “Crystal structure of the Drosophila FTZ-F1 LBD/FTZ complex identifies a new class of ligand-independent nuclear receptor” Journal of biological chemistry, 286(36), 31225-31 (2011.09) (* co_correspondence)
  • 46. Ju Ho Youn, Man Sup Kwak, Jie Wu, Eun Sook Kim, Yeounjung Ji, Hyun Jin Min, Ji-Ho Yoo, Ji Eun Choi, Hyun-Soo Cho, and Jeon-Soo Shin “Identification of lipopolysaccharide-binding peptide regions within HMGB1 and their effects on subclinical endotoxemia in a mouse model” European Journal of Immunology 41(9), 2753-62 (2011.09)
  • 45. Jin Pyo Hong, Tae-im Kim, Jae Lim Chung, Huang David, Hyun-Soo Cho, Eung kweon Kim “Analysis of deposit depth and morphology in granular corneal dystrophy type 2 using fourier domain optical coherence tomography” Cornea 30(7), 729-38 (2011.07)
  • 44. Yongbin Xu, Saemee Song, Arne Moeller, Nahee Kim, Shunfu Piao, Se-Hoon Sim, Mooseok Kang, Wookyung Yu, Hyun-Soo Cho, Iksoo Chang, Kangseok Lee, and Nam-Chul Ha “Functional Implications of an Intermeshing Cogwheel-Like Interaction between TolC and MacA in the Action of Macrolide-Specific Efflux Pump MacAB-TolC” Journal of biological chemistry, 286(15), 13541-9 (2011.04)
  • 43. Bo-Young Yun, Youngbin Xu, Shunfu Piao, Nahee Kim, Jeong-Hyun Yoon, Hyun-Soo Cho, Kangseok Lee and Nam-Chul Ha “Periplasmic domain of CusA in an Esherichia coli Cu/Ag transporter has metal binding sites” The Journal of Microbiology, 48(6), 829-835 (2010.12)
  • 42. Ji Won Um, Eunju Im, Hyun Jung Lee, Boram Min,Lang Yoo, Jiho Yoo, Hermann Lu¨bbert, Christine Stichel-Gunkel, Hyun-Soo Cho, Jong Bok Yoon,and Kwang Chul Chung “Parkin Directly Modulates 26S Proteasome Activity” The Journal of Neuroscience, 30(35), 11805-11814 (2010.09)
  • 41. Jae Hwan Lee, Stephen M. Cristol, Woon Cho Kim, Eui Sang Chung, Hungwon Tchah, Man Soo Kim, Chung Mo Nam, Hyun-Soo Cho, Eung Kweon Kim, “Prevalence of granular corneal dystrophy type II (Avellino corneal dystrophy) in the Korean population” Ophthalmic Epidemiology, 17, 160-165 (2009.06)
  • 40. Hyung-In Moon, Tae-im Kim, Hyun-Soo Cho and Eung Kweon Kim “Identification of potential and selective collagenase, gelatinase inhibitors from Crataegus pinnatifida” Bioorganic & Medicinal Chemistry Letters 20(3), 991-993 (2010.02)
  • 39. Byoung Jin Ha, Tae-im Kim, Seung-il Choi, R. Doyle Stulting, Dong Ho Lee, Hyun-Soo Cho and Eung Kweon Kim “Mitomycin C Does Not Inhibit Exacerbation of Granular Corneal Dystrophy Type II Induced by Refractive Surface Ablation” Cornea 29(5), 490-496 (2010.05)
  • 38. Eun-Young Won, Kiweon Cha, Jung-Sue Byun, Sumi Shin, Byungchan Ahn, Young Ho Kim, Amanda J. Rice, Thomas Walz, Byoung S. Kwon, and Hyun-Soo Cho “The structure of the trimer of human 4-1BB ligand is unique among members of the TNF superfamily” Journal of Biological Chemistry, 282, 9202-9210 (2010.03)
  • 37. Shunfu Piao, Xiao Lig Jin, Bo-Young Yun, Nahee Kim, Hyun-Soo Cho, Minoru Fukuda, Heeseob Lee, Nam-Chul Ha “Crystal structure and functional insight of HP0420-homolog from Helicobacter felis” BBRC, 394 (4), 940-946 (2010.04)
  • 36. Seung-il Choi, Yeong-Min Yoo, Bong-Yoon Kim, Tae-im Kim, Hyun-ju Cho, So-yoen Ahn, Hyung Keun Lee, Hyun-Soo Cho, and Eung Kweon Kim “cDNA Microarray Analysis Reveals the Involvement of TGF-β Receptor- and Integrin-Mediated Signaling Pathways in the Pathogenesis of Granular Corneal Dystrophy II” Invest. Ophthalmol.Vis. Sci. 51(4) 1832-1847 (2010.04)
  • 35. Yong Soon Cho, Jae Il Lee, Dongkyu Shin, Hyun Tae Kim, Ha Yun Jung, Tae Gyu Lee, Lin-Woo Kang, Yeh-Jin Ahn, Hyun-Soo Cho, Yong-Seok Heo, ”Molecular mechanism for the regulation of human ACC2 through phosphorylation by AMPK” BBRC, 391(1) 187-192 (2010.01)
  • 34. Dongeun Yong, Mark A. Toleman, Christian G. Giske, Hyun-Soo Cho, Kristina Sundman, Kyungwon Lee and Timothy R. Walsh “Characterization of a New Metallo-β-lactamase gene, blaNDM-1, and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India” antimicrobial agents and chemotherapy, 53, 5046-5054 (2009.12)
  • 33. Bong-Yoon Kim, James A. Olzmann, Seung-il Choi, So Yeon Ahn, Tae-im Kim, Hyun-Soo Cho and Eung Kweon Kim “Corneal dystrophy-associated R124H mutation disrupts TGFBI interaction with periostin and causes mislocalization to the lysosome” Journal of Biological Chemistry, 284, 19580-91 (2009.07)
  • 32. Seung-il Choi, Tae-im Kim, Kyu Seo Kim, Bong-Yoon Kim, So-yeon Ahn, Hyun-ju Cho, Hyung Keun Lee, Hyun-Soo Cho and Eung Kweon Kim “Decreased Catalase Expression and Increased Susceptibility to Oxidative Stress in Primary Cultured Corneal Fibroblasts from Patients with Granular Corneal Dystrophy Type II” The American Journal of Pathology, 175, 248-61 (2009.07)
  • 31. Jaewoo Song, Ilaria Guella, Ki-Yung Kwon, Hyun-Soo Cho, Rojin Park, Rosanna Asselta and Jong Rak Choi “A novel in-frame deletion in the factor V C1 domain associated with severe coagulation factor V deficiency in a Korean family” BLOOD COAGULATION & FIBRINOLYSIS, 20, 150-156 (2009.03)
  • 30. Sunggeon Ko, Eun Young Yu, Joon Shin, Hyun Hee Yoo, Toshiyuki Tanaka, Woo Taek Kim, Hyun-Soo Cho, Weontae Lee and In Kwon Chung “Solution structure of the DNA binding domain of rice telomere binding protein RTBP1” Biochemistry, 48 (5), 827-838 (2009.02)
  • 29. Yun Jae Kim, Sun-Shin Cha, Hyun Sook Lee, Yong Gu Ryu, Seung Seob Bae, Yona Cho, Hyun-Soo Cho, Sang-Jin Kim, Suk-Tae Kwon, Jung-Hyun Lee, and Sung Gyun Kang “Sensing Domain and Extension Rate of a Family B-type DNA Polymerase Determine the Stalling at a Deaminated Base”, Applied Microbiology and Biotechnology, 18, 1377-1385 (2008.08)
  • 28. Sunggeon Ko, Sung-Hoon Jun, Hansol Bae, Jung-Sue Byun, Woong Han, Heeyoung Park, Seong Wook Yang, Sam-Yong Park, Young Ho Jeon, Chaejoon Cheong, Woo Taek Kim, Weontae Lee, and Hyun-Soo Cho “Structure of the DNA Binding Domain of NgTRF1 Reveals Unique Features of Plant Telomere Binding Proteins”, Nucleic Acids Research, 36 (8), 2739-2755 (2008.03)
  • 27. Suhng Wook Kim, Dong-Uk Kim, Jin Kwang Kim, Lin-Woo Kang, and Hyun-Soo Cho “Crystal structure of Pfu, the high fidelity DNA polymerase from Pyrococcus furiosus”, International Journal of Biological Macromolecules 42, 356-361 (2008.05)
  • 26. Dong-Uk Kim, Ji-Ho Yoo, Yong Joo Lee, Kwan Soo Kim and Hyun-Soo Cho “Structural analysis of sialyltransferase PM0188 from Pasteurella Multocida complexed with donor analogue and acceptor sugar”, BMB reports 41 (1), 48-54 (2008.01)
  • 25. Ji-Ho Yoo, EungKweon Kim, Jongsun Kim and Hyun-Soo Cho “Crystallization and preliminary crystallographic analysis of the fourth FAS1 domain of human BigH3”, Acta Crystallograph. Sect. F Struct. Biol. Cryst. Commun. F63, 893-895 (2007.09)
  • 24. Jung-Sue Byun, Jin-Kyu Rhee, Nam Doo Kim, JeongHyeok Yoon, Dong-Uk Kim, Eunhee Koh, Jong-Won Oh, and Hyun-Soo Cho “Crystal structure of hyperthermophilic esterase EstE1 and the relationship between its dimerization and thermostability properties”, BMC Structural Biology, 7(1), 47, 1472-6807 (2007.07)
  • 23. Eunmi Hong, Hyang Mi Lee, Hyunsook Ko , Dong-Uk Kim, Byoung-Young Jeon, Jinwon Jung, Joon Shin, Sung-Ah Lee, Yangmee Kim, Young Ho Jeon, Chaejoon Cheong, Hyun-Soo Cho* and Weontae Lee* (*co_correspondence) “Structure of an Atypical Orphan Response Regulator Protein Supports a New Phosphorylation-Independent Regulatory Mechanism”, Journal of Biological Chemistry 282, 20667-20675 (2007.07)
  • 22. Seulki Kim, Han le Kim, Jae-Sung Woo, Hyun-Soo Cho, Yunjin Jung, Seung-Taek Lee and Nam-Chul Ha “High Level Production of human Protein Tyrosine Kinase-6 in Insect Cells Using Drosophila Peptidoglycan Recognition Protein-LB as a fusion protein”, Journal of Life Science 17, 179-184 (2007.02)
  • 21. Yun Jina, Ho-Yong Chung, Seong-jun Kim, Hyun-Soo Cho and Jongwon Oh “Purification and Characterization of the Functional Catalytic Domain of PKR-like Endoplasmic Reticulum Kinase Expressed in Escherichia coli”, Journal of Microbiology and Biotechnology (2006.05)
  • 20. Jin-Kyu Rhee, Do-Yun Kim, Dae-Gyun Ahn, Jung-Hyuk Yun, Seung-Hwan Jang, Hang-Cheol Shin, Hyun-Soo Cho, Jae-Gu Pan, and Jong-Won Oh “Analysis of the Thermostability Determinants of Hyperthermophilic Esterase EstE1 Based on Its Predicted Three-Dimensional Structure”, APPLIED AND ENVIRONMENTAL MICROBIOLOGY 72, 3021–3025 (2006.04)
  • 19. Eunhee Koh, Taehyo Kim, Hyun-Soo Cho “Mean curvature as a major determinant of b-sheet propensity”, Bioinformatics 22, 297-302 (2006.02)
  • 18. Hyang Mi Lee, Eunmi Hong, Byoung-Young Jeon, Dong-Uk Kim, Jung-Sue Byun, Weontae Lee, Hyun-Soo Cho “Crystallization and Preliminary X-ray Crystallographic Study of HP1043, a Helicobacter pylori Orphan Response Regulator”, BBA- PROTEINS AND PROTEOMICS 1764, 989-991 (2006.05)
  • 17. Jung-Sue Byun, Dong-Uk Kim, Byungchan Ahn, Byoung Se Kwon, and Hyun-Soo Cho “Crystallization and preliminary X-ray crystallographic analysis of the extracellular domain of the 4-1BB ligand, a member of the TNF family”, Acta Crystallograph. Sect. F Struct. Biol. Cryst. Commun. 62, 23-25 (2006.01)
  • 16. Jung-Sue Byun, Jin-kyu Rhee, Dong-Uk Kim, Jong-Won Oh, Hyun-Soo Cho “Crystallization and preliminary X-ray crystallographic analysis of EstE1, a new and thermostable esterase cloned from a metagenomic library”, Acta Crystallograph. Sect. F Struct. Biol. Cryst. Commun. 62, 145-147 (2006.01)
  • 15. Dong-Uk Kim, Ji-Ho Yoo, Kang Ryu and Hyun-Soo Cho “Crystallization and preliminary X-ray crystallographic analysis of the a-2,6-sialyltransferase PM0188 from Pasteurella multosida”, Acta Crystallograph. Sect. F Struct. Biol. Cryst. Commun. 62, 142-144 (2006.01)
  • 14. Antony W. Burgess, Hyun-Soo Cho, Charles Eigenbrot, Kathryn M. Ferguson Thomas P.J. Garrett, Daniel J. Leahy, Mark A. Lemmon, Mark X. Sliwkowski Colin W. Ward, and Shigeyuki Yokoyama “Review An Open-and-Shut Case ? Recent Insights into the Activation of EGF/ErbB Receptors”, Molecular Cell 12, 541-552 (2003.09). (IF 14.194)
  • 13. Hyun-Soo Cho, Karen Mason, Kasra X. Ramyar, Ann Marie Stanley, Sandra G. Gabelli, Dan W. Denney Jr., Daniel J. Leahy “Structure of the Extracellular Region of HER2 Alone and Complexed with the Herceptin Fab”, NATURE 421, 756-760 (2003.02) (IF 36.101)
  • 12. Kathryn M. Ferguson, Mitchell B. Berger, Jeannine M. Mendrola, Hyun-Soo Cho, Daniel J. Leahy and Mark A. Lemmon “EGF Activates Its Receptor by Removing Interactions that Autoinhibit Ectodomain Dimerization”, Molecular Cell 11, 1-20 (2003.02) (IF 14.194)
  • 11. Hyun-Soo Cho, Daniel J. Leahy “Structure of the Extracellular Region of HER3 Reveals an Interdomain Tether”, SCIENCE 297, 1330-1333 (2002.08). (IF 31.364)
  • 10. Hee-Sup Lee, Min-Sung Kim, Hyun-Soo Cho, Jung-In Kim, Tae-Jip Kim, Ji-Hye Choi, Cheonseok Park, Heung-Soo Lee, Byung-Ha Oh*, Kwan-Hwa Park, "Cyclomaltodextrinase, neopullulanase, and maltogenic amylase are nearly indistinguishable from each other", J. Biol. Chem. 277, 21891-21897 (2002.03)
  • 9. Kyung Seok Oh, Sun-Shin Cha, Do-Hyung Kim, Hyun-Soo Cho, Nam-Chul Ha, Gildon Choi, Jin Yong Lee, P. Tarakeshwar, Hyeon S. Son, Kwan Yong Choi*, Byung-Ha Oh*, Kwang S. Kim*, "Role of Catalytic Residues in Enzymatic Mechanisms of Homologous Ketosteroid Isomerases", Biochemistry 39, 13891-13896 (2000.11)
  • 8. Jeong-Sun Kim, Sun-Shin Cha, Hyun-Ju Kim, Tae-Jip Kim, Nam-Chul Ha, Sang-Taek Oh, Hyun-Soo Cho, Moon-Ju Cho, Myo-Jeong Kim, Hee-Seob Lee, Jung-Wan Kim, Kwan Yong Choi, Kwan-Hwa Park, Byung-Ha Oh, "Crystal Structure of a Maltogenic Amylase Provides Insights into a Catalytic Versatility", J. Biol. Chem. 274, 26279-26286 (1999).
  • 7. Hyun-Soo Cho, Nam-Chul Ha, Gildon Choi, Hyun-Ju Kim, Donghan Lee, Kyung Seok Oh, Kwang S. Kim, Weontae Lee, Kwan Yong Choi, Byung-Ha Oh,"Crystal Structure of △5-3-Ketosteroid Isomerase from Pseudomonas testosteroni in Complex with Equilenin Settles the Correct Hydrogen Bonding Scheme for Transit